Sarcoma cancer recurrence
Abstract An 8-year-old spayed female Netherland Dwarf sarcoma cancer recurrence presented with a two-month history of dyspnea and snoring.
A computed tomography CT scan of the head revealed mass lesions in the right nasal cavity. Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma.
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On the basis of this diagnosis, radiotherapy was planned and consisted of eight fractions of 6 Gy administered once a week. After the completion of radiation therapy, the soft tissue density in the right nasal cavity, as detected by CT, significantly decreased.
The prognosis has remained good for over 3 years after treatment. This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.
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Keywords: adenocarcinoma, intranasal tumor, rabbit, radiation therapy Numerous infectious agents cause upper respiratory tract diseases in rabbits, and these include mainly bacterial organisms, such as Pasteurella multocida, Bordetella bronchiseptica and Pseudomonas species; however, some cases may involve viral, fungal or parasitic pathogens as well. Noninfectious causes of upper respiratory tract disorders include traumatic injury and dental disease. The only neoplastic disease of the nasal cavity reported in rabbits is an anecdotal report of a carcinoma of the nasal turbinates [ 7 ].
The first choice of therapy for intranasal tumors in dogs and cats is either radiation therapy alone or a combination of surgery and radiation therapy [ 191214 ]. Additionally, chemotherapy has been used as the primary treatment [ 26 ] and as an adjuvant therapy [ 34 ].
However, there have been no reports of nasal tumors in rabbits, and the therapeutic efficacy, biological behavior and prognosis are unknown.
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Here, the authors evaluated a rabbit presenting with dyspnea and snoring, and an intranasal mass detected by computed tomography CT was histologically diagnosed as an adenocarcinoma. This report describes the treatment of this case, which has been maintained successfully for a long period by a combination sarcoma cancer recurrence exenteration of the intranasal mass and localized radiotherapy.
An sarcoma cancer recurrence spayed female Netherland Dwarf rabbit, weighing 1.
Another private veterinary clinic had administered antibiotics via a subcutaneous injection and nebulization. Three weeks later, discharge from the right nasal cavity was observed during consultation, and a sample collected for bacterial culture yielded a negative result.
Because of the worsening dyspnea, a CT scan was performed under anesthesia for evaluation of the nasal sarcoma cancer recurrence. Images from the CT scan revealed two mass lesions of soft tissue density within the right nasal cavity Fig.
Thereafter, the rabbit was referred to our clinic for further treatment. A complete blood cell count and serum biochemical sarcoma cancer recurrence showed no abnormal findings. Thoracic and abdominal radiographs revealed no abnormal sarcoma cancer recurrence, including no evidence of pulmonary metastasis.
Based on the CT images, exenteration of the intranasal mass lesions was performed.